Organic potassium salts
Medchemexpress LLC Acesulfame (potassium) | 55589-62-3 | 99.4% | 10 G
Acesulfame potassium is a synthetic sweetener that can affect cognitive function by altering neurometabolic functions. It can also suppress autophagic degradation of PD-L1 in cancer cells, which may be related to immune evasion. This product is suitable for research on neurological diseases, metabolic disorders, cancer, and immune evasion.
- Research applications include neurological diseases, metabolic disorders, cancer, and immune evasion.
- Upregulates PD-L1 protein levels in RIL-175 and SK-Hep1 cells.
- Increases granzyme B production in co-cultured T cells.
- Activates ERK1/2-mTORC1-ULK1 pathway to suppress autophagic degradation of PD-L1.
- Inhibits mitochondrial metabolism and impairs neuroprotective functions in SH-SY5Y cells.
- Affects body weight and gut microbiome composition in male CD-1 mice.
- Alters neurometabolic functions in C57BL/6J mice.
Medchemexpress LLC PD 144418 oxalate | 1794760-28-3 | 98.65% | 372.41 | 50 MG
PD 144418 oxalate is a highly affine, potent, and selective sigma 1 (σ1) receptor ligand. With Ki values of 0.08 nM for σ1 and 1377 nM for σ2, it does not show significant affinity for other receptors, ion channels, or enzymes. This compound exhibits potential antipsychotic activity.
- Highly affine, potent, and selective sigma 1 (σ1) receptor ligand
- Devoids significant affinity for other receptors, ion channels, and enzymes
- Shows potential antipsychotic activity
- Reverses NMDA-induced increase in cyclic GMP (cGMP) in rat cerebellar slices in vitro
- Potentiates the decrease in 5-hydroxytryptophan caused by Haloperidol in the mesolimbic region in vitro
- Antagonizes Mescaline-induced scratching in male CD-1 mice in vivo
Medchemexpress LLC GJ071 oxalate | 1216676-34-4 | 99.7% | C20H29N3O7S | 10MG
GJ071 oxalate is a research-grade small molecule that induces ATM kinase activity in ataxia telangiectasia (A-T) cells carrying homozygous TGA or TAG stop codons. Supplied as a solid with high reported purity, it is intended for in vitro biochemical and cellular studies; follow supplier handling and storage recommendations.
eMolecules 95-92-1 | Diethyl oxalate | Combi-Blocks | MFCD00009119 | 146.142 | C6H10O4 | 98.000 | CCOC(=O)C(=O)OCC | 1kg | 290699379
Diethyl oxalate | Combi-Blocks | 95-92-1 | MFCD00009119 | 146.142 | C6H10O4 | 98.000 | CCOC(=O)C(=O)OCC | 1kg | 290699379
Medchemexpress LLC Naloxegol oxalate | 1354744-91-4 | MFCD29472292 | 99.9% | 741.82 | C36H55NO15 | 10 MG
Naloxegol oxalate is the oxalate salt of naloxegol, a peripherally selective μ-opioid receptor antagonist used in research to study and mitigate opioid-induced constipation. The product is supplied as a high-purity solid and as a DMSO solution for in vitro and preclinical applications.
- Peripherally selective μ-opioid receptor antagonist.
- High purity (99.9%), suitable for analytical and biological assays.
- Available as 10 mg solid packs and as 10 mM solution in DMSO.
- Commonly used to study opioid-induced gastrointestinal effects and receptor pharmacology.
- Chemical identifiers: CAS 1354744-91-4; molecular weight 741.82.
Medchemexpress LLC Bleximenib oxalate | 2866179-95-3 | 98.0% | 689.82 | C34H52FN7O7 | 10 MG
Bleximenib oxalate is the oxalate salt of bleximenib, an orally active and selective menin-KMT2A inhibitor used for preclinical oncology research. The compound is supplied as a light yellow solid with manufacturer-reported purity, solubility, and recommended storage conditions to support experimental handling and formulation.
- Purity 98.0%.
- Light yellow solid physical form.
- Selective menin-KMT2A inhibitor for preclinical studies.
- Soluble in DMSO (100 mg/mL) with published in vivo formulation protocols.
- Recommended storage for powder and solutions to maintain stability.
- Available in small research pack sizes for dosing flexibility.
eMolecules 95-92-1 | Diethyl oxalate | Combi-Blocks | MFCD00009119 | 146.142 | C6H10O4 | 98.000 | CCOC(=O)C(=O)OCC | 500g | 296394161
Diethyl oxalate | Combi-Blocks | 95-92-1 | MFCD00009119 | 146.142 | C6H10O4 | 98.000 | CCOC(=O)C(=O)OCC | 500g | 296394161
Medchemexpress LLC N,N'-Dinitrosopiperazine | 140-79-4 | 99.9% | 144.13 | 100 MG
N,N'-Dinitrosopiperazine (DNP) is identified as a carcinogen with specificity for nasopharyngeal epithelium, facilitating nasopharyngeal carcinoma (NPC) metastasis. It regulates multiple signaling pathways through protein phosphorylation, including LYRIC at serine 568.
- Specific carcinogen for nasopharyngeal epithelium
- Facilitates NPC metastasis
- Regulates multiple signaling pathways through protein phosphorylation
- Induces cell invasion and motility in a dose-dependent manner in vitro
- Increases expression of phospho-LYRIC s568 and LYRIC in CNE1 cells
- Promotes NPC metastasis in vivo by inhibiting cell motility and invasion
- Induces LYRIC phosphorylation at serine 568 in vivo
Medchemexpress LLC Acesulfame potassium | 55589-62-3 | 99.38% | 50 G
Acesulfame potassium | 55589-62-3 | 99.38% | 50 G
eMolecules 95-92-1 | Diethyl oxalate | Combi-Blocks | MFCD00009119 | 146.142 | C6H10O4 | 98.000 | CCOC(=O)C(=O)OCC | 25g | 296394160
Diethyl oxalate | Combi-Blocks | 95-92-1 | MFCD00009119 | 146.142 | C6H10O4 | 98.000 | CCOC(=O)C(=O)OCC | 25g | 296394160
eMolecules 95-92-1 | Diethyl oxalate | Combi-Blocks | MFCD00009119 | 146.142 | C6H10O4 | 98.000 | CCOC(=O)C(=O)OCC | 100g | 290699377
Diethyl oxalate | Combi-Blocks | 95-92-1 | MFCD00009119 | 146.142 | C6H10O4 | 98.000 | CCOC(=O)C(=O)OCC | 100g | 290699377
Cayman Chemical Xanomeline oxalate
A potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively); has antipsychotic-like activities in rats and Cebus monkeys; enhances memory function and has utility in treating Alzheimer’s Disease
Cayman Chemical Xanomeline oxalate
A potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively); has antipsychotic-like activities in rats and Cebus monkeys; enhances memory function and has utility in treating Alzheimer’s Disease
Apexbio Technology LLC Malachite green oxalate 2437-29-8 100mg
Malachite green oxalate (CAS 2437-29-8) is a triphenylmethane dye commonly utilized for quantifying phosphate release in enzymatic assays Mechanistically it functions as a selective inhibitor of IKBKE kinase resulting in reduced phosphorylation and activity of downstream effectors including I B p65 and IRF3 Experimental studies have demonstrated its ability to suppress tumor cell proliferation and interfere with related signaling pathways in various cell lines and animal models Malachite green oxalate serves as a valuable tool for investigating tumorigenic mechanisms and exploring targeted therapeutic strategies
Medchemexpress LLC GJ071 oxalate | 1216676-34-4 | 99.7% | 455.53 g/mol | C20H29N3O7S | 5 MG
GJ071 oxalate is a research-grade small molecule reported to induce ATM kinase activity in ataxia telangiectasia (A-T) cells carrying homozygous TGA or TAG stop codons. Supplied as the oxalate salt for laboratory research use.
- Induces ATM kinase activity in A-T cells with TGA or TAG stop codons.
- High purity: 99.74%.
- Molecular formula: C20H29N3O7S; molecular weight: 455.53 g/mol.
- Available in small-scale laboratory quantities (1 mg-100 mg).
- Suitable for cellular research applications; soluble in DMSO.